Serostim HGH Kit instructions:
This section explains how to give yourself a Serostim HGH injection. It may seem complicated, but after you've given yourself the first injection, it will get easier. Serostim® injections can fairly easily be given because Serostim hgh ® is injected under the skin (subcutaneously). Many patients self-inject many types of drugs subcutaneously. This type of injection is less penetrating than injections that are given directly into a vein or muscle (intravenous or intra muscular injections). If you are interested in receiving a Serostim® injection instruction video, please call 800-714-2437.
Your Needle and Syringe
It's important to know all the different pieces used in giving a subcutaneous injection – and how they work.
You have two needle sizes. The longer needle is for mixing Serostim® and the shorter needle is for giving yourself the injection.
This is the plastic tube that holds the liquid to be injected. Just like a ruler, it has lines to tell you how much liquid is inside. The tip of the barrel should have a plastic protector.
This plastic cover keeps the needle sterile and prevents accidental "sticks." Plunger
This is the rod-like piece that slides in and out of the barrel. You should hold the end of the plunger.
This is the part of the needle that connects the needle to the syringe barrel.
Now you're ready to learn how to give yourself an injection. But, before you begin, organize all of your injection supplies .Injection Supplies
Gather the following items when you are ready to prepare to inject your dose:
This vial contains the drug in a freeze-dried pellet.
Sterile Water for Injection Vial
This vial holds the sterile water that you will mix with Serostim® to dissolve it.
You will only need one syringe, but you will use it twice: to add sterile water to the Serostim® vial and to give yourself the injection.
You have two needles: a longer needle to add sterile water to the Serostim® vial and withdraw the drug prior to injection, and a shorter needle to give yourself the injection.
You will use these to clean your skin where you intend to inject. You will also use the swabs to wipe off the vial tops.
Band-Aid® or Adhesive Bandage and gauze pad (if desired)
After injecting yourself, you may want to cover the injection site with a Band-Aid® or an adhesive bandage and gauze pad.
Make sure all the above items are still in unopened packages. If you find a needle or syringe packet open, do not use it. Dispose of it in your used needle/syringe box.
Used Needle/Syringe Box (Sharps Container)
Your healthcare provider or pharmacy that distributes Serostim® may have provided you with a red safety box. You can also use a coffee can with a snap-on lid or another strong container to create a "used needle box." You will put used needles and syringes into it to protect you and other people from getting stuck with them and to prevent the spread of HIV and other infections.
Have these ready if a friend or family member will be giving you the injection. You do not need gloves if you'll be injecting yourself.
Now that you have organized your supplies, select a good work surface. A bathroom or kitchen counter may be a good place. The surface should be flat, and the room should have lots of bright light so you can see well. Before you begin, always make sure the work area is clean and wash your hands .Injecting Serostim (rDNA Orign) for injection)
Remember, it is recommended to inject Serostim® right before you go to bed. Typically more growth hormone is secreted at night than during the day.
Get Your Serostim® [somatropin (rDNA origin) for injection] Injection Supplies
Clean the Work Surface
Wash Your Hands
Wash your hands with soap and water. If someone else is giving you the injection, he or she should put on a pair of disposable gloves now.
Serostim HGH Reconstitution
Remove Flip Tops from Drug and Sterile Water Vials
Remove the flip tops from drug and sterile water vials. Throw the tops away. You can use your regular wastebasket.
Clean both rubber stoppers with a fresh alcohol swab. You can also throw this swab in your regular wastebasket.
Do not touch the vial tops with your hands or gloves.
IF YOU TOUCHED THE SEROSTIM HGH VIAL TOPS AFTER CLEANING THEM: Simply use a new alcohol swab to wipe off the vial tops that you touched. Then continue with the next step in the instructions.
Twist the Larger Needle Onto Syringe
Unwrap the syringe.
Unwrap the larger needle. Do not touch the hub of the needle where it connects to the syringe.
Take the plastic tip protector from the syringe (if it has one).
Hold the syringe by its cap and twist tightly into place on the syringe. Keep the needle cap on as you do this.
IF YOU TOUCH OR DROP THE HUB OF THE NEEDLE OR THE BOTTOM OF THE SYRINGE BEFORE THEY ARE CONNECTED: Dispose of them in your red safety box. Start over with a new needle and syringe.
Pull Plunger/Remove Needle Cap
Pull back on the plunger in the syringe until it reaches the 1cc line on the barrel unless your medical provider has designated a different dose.
Keep the needle cap on the needle.
Do not touch the now exposed plunger.
Hold the syringe in one hand. Use your other hand to pull the needle cap straight off the needle (do not twist the cap as you pull).
If the needle and the syringe come apart — and they have not touched anything — simply twist them back together again.
If the needle and/or syringe have touched anything, dispose of them in your red safety box. Then, simply start over again from Step 2.
Set the needle cap aside. You will need it again later.
Fill the Syringe With Sterile Water
Place the vial of sterile water on your clean work surface.
Push the needle straight down through the middle of the rubber stopper on top of the vial.
Push on the syringe plunger all the way down; this will push 1cc of air into the vial. You'll feel a little pressure.
While holding the plunger down, pick up the vial and the syringe with your other hand and turn it upside down. Now, slide the needle tip below the level of water in the vial.
Release the plunger. The syringe barrel fills up with water by itself. You can help it along by pulling back on the plunger until it reaches the 1cc mark on the syringe barrel. If air bubbles get in, tap the barrel with your fingertips, then gently push the plunger in to move the air bubble(s) back into the vial.
When you have 1cc of water in the syringe and it's clear of air bubbles, wiggle the vial off the needle, being careful not to touch the needle tip. Do not put the syringe down.
Throw the empty water vial away in your regular wastebasket.
Preparing Serostim® [somatropin (rDNA origin) for injection]
Now you will mix the sterile water with the drug provided in the Serostim® vial to produce Serostim®. At this point, you should be holding the needle and syringe containing 1cc of sterile water without any air bubbles.Step 8Slowly Inject the Sterile Water Against the Inner Side of the Serostim® Vial
Place the vial of Serostim HGH on your clean surface.
Holding the water-filled syringe by the barrel, push the needle, at a slight angle to the rubber stopper, all the way down into the top of the Serostim® vial. The needle tip should rest against the wall of the vial. Push the syringe plunger gently and slowly to allow the water to flow down the side of the vial. Do not squirt the water onto the pellet. This will make the drug solution foamy and hard to use .Safety Profile
Serostim® [somatropin (rDNA origin) for injection] is the only growth hormone approved by the U.S. Food and Drug Administration for the treatment of AIDS wasting or cachexia. This indication is based on the analysis of changes in body weight and lean body mass in studies of up to 12 weeks in duration. The continued use of Serostim® treatment should be reevaluated in patients who continue to lose weight in the first two weeks of treatment.
Click here for Serostim HGH Full Prescribing Information.
Serostim - HGH, when taken as prescribed, is generally well tolerated. In clinical studies, 1.5% of patients stopped using Serostim® due to drug-related side effects. The most common adverse reactions to Serostim® are increased tissue turgor (generally swelling of hands and feet) and musculoskeletal discomfort (pain, swelling or stiffness). Generally mild to moderate in severity, these symptoms usually resolve spontaneously with continued treatment or are effectively managed with analgesic therapy. When unresponsive to symptomatic therapy, these side effects may also be managed by reducing the total daily dose of Serostim® or the number of doses given per week. Elevations in mean blood glucose levels can also occur. Patients with other risk factors for glucose intolerance should be monitored closely.
Serostim® must be given with concomitant antiviral therapy. There is no evidence of HIV replication with Serostim® therapy in the presence of any of the currently available nucleoside analogues in vitro. In the controlled clinical trials, no significant growth hormone-associated increase in viral burden was observed. However, growth hormone has been shown to increase HIV replication in some experimental systems.
Serostim® therapy should be carried out under the regular guidance of a physician who is experienced in the diagnosis and management of AIDS. Inadequate nutritional intake, malabsorption and hypogonadism, which are common in individuals with AIDS and which may contribute to catabolism and weight loss, should also be monitored and treated. Patients should contact their physician should they experience any side effects or discomfort during treatment with Serostim®. Serostim®, like other growth hormones, should generally not be used in patients with acute critical illness in intensive care units since safety has not been established in this situation.
Rebuilding and retaining lean body mass is possible with Serostim® treatment. Muscle, organ tissue and body fluids are components of lean body mass. However, the impact of treatment-induced improvements in body weight and lean body mass on survival has not been established in placebo-controlled trials.